Genetic and Functional Studies of the Intervertebral Disc: A Novel Murine Intervertebral Disc Model
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چکیده
منابع مشابه
Genetic and Functional Studies of the Intervertebral Disc: A Novel Murine Intervertebral Disc Model
Intervertebral disc (IVD) homeostasis is mediated through a combination of micro-environmental and biomechanical factors, all of which are subject to genetic influences. The aim of this study is to develop and characterize a genetically tractable, ex vivo organ culture model that can be used to further elucidate mechanisms of intervertebral disc disease. Specifically, we demonstrate that IVD di...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0112454